Ensemble machine learning identifies genetic loci associated with future worsening of disability in people with multiple sclerosis
- Creator: Fuh-Ngwa, Valery , Zhou, Yuan , Melton, Phillip E. , van der Mei, Ingrid , Charlesworth, Jac C. , Lin, Xin , Zarghami, Amin , Broadley, Simon A. , Ponsonby, Anne-Louise , Simpson-Yap, Steve , Lechner-Scott, Jeannette , Taylor, Bruce V.
- Resource Type: journal article
- Date: 2022
PATJ low frequency variants are associated with worse ischemic stroke functional outcome: a genome-wide meta-analysis
- Creator: Mola-Caminal, Marina , Carrera, Caty , Muiño, Elena , Rodríguez-Campello, Ana , Ois, Angel , Cuadrado-Godia, Elisa , Vivanco-Hidalgo, Rosa M. , Hernandez-Guillamon, Mar , Solé, Montse , Delgado, Pilar , Bustamante, Alejandro , García-Berrocoso, Teresa , Soriano-Tárraga, Carolina , Mendióroz, Maite , Castellanos, M , Serena, J , Martí-Fàbregas, J , Segura, T , Serrano-Heras, G , Obach, V , Ribó, M , Molina, CA , Alvarez-Sabín, J , Giralt-Steinhauer, Eva , Palomeras, E , Freijo, M , Font, MA , Rosand, J , Rost, NS , Gallego-Fabrega, C , Lee, JM , Heitsch, L , Ibanez, L , Cruchaga, C , Díaz-Navarro, Rosa M. , Phuah, CL , Lemmens, R , Thijs, V , Lindgren, A , Maguire, Jane , Rannikmae, K , Sudlow, CL , Jern, Christina , Stanne, TM , Lorentzen, E , Tur, Silvia , Muñoz-Narbona, L , Dávalos, A , López-Cancio, E , Worrall, BB , Woo, D , Kittner, SJ , Mitchell, BD , Montaner, J , Roquer, J , Krupinski, J , Jiménez, Carmen , Estivill, X , Rabionet, R , Vives-Bauzá, C , Fernández-Cadenas, I , Jimenez-Conde, J , Medina-Dols, Aina , Cullell, Natalia , Torres-Aguila, Nuria P.
- Resource Type: journal article
- Date: 2019
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
- Creator: Davies, Gail , Lam, Max , Liewald, David C. M. , Knopman, DS , Kochan, NA , Konte, B , Kwok, JB , Le Hellard, S , Lee, T , Lehtimaki, T , Li, S-C , Liu, T , Koini, M , Okely, Judith A. , London, E , Longstreth, WT , Lopez, OL , Loukola, A , Luck, T , Lundervold, AJ , Lundquist, A , Lyytikainen, L-P , Martin, NG , Montgomery, GW , Ahola-Olli, Ari V. , Murray, AD , Need, AC , Noordam, R , Nyberg, L , Ollier, W , Papenberg, G , Pattie, A , Polasek, O , Poldrack, RA , Psaty, BM , Barnes, Catriona L. K. , Reppermund, S , Riedel-Heller, SG , Rose, RJ , Rotter, JI , Roussos, P , Rovio, SP , Saba, Y. , Sabb, FW , Sachdev, PS , Satizabal, CL , Bertram, Lars , Schmid, M , Scott, Rodney J. , Scult, MA , Simino, J , Slagboom, PE , Smyrnis, N , Soumare, A , Stefanis, NC , Stott, DJ , Straub, RE , Bis, Joshua C. , Sundet, K , Taylor, AM , Taylor, KD , Tzoulaki, I , Tzourio, C , Uitterlinden, A , Vitart, V , Voineskos, AN , Kaprio, J , Wagner, M , Burdick, Katherine E. , Wagner, H , Weinhold, L , Wen, KH , Widen, E , Yang, Q , Zhao, W , Adams, HHH , Arking, DE , Bilder, RM , Bitsios, P , Christoforou, Andrea , Boerwinkle, E , Chiba-Falek, O , Corvin, A , De Jager, PL , Debette, S , Donohoe, G , Elliott, P , Fitzpatrick, AL , Gill, M , Glahn, DC , DeRosse, Pamela , Hagg, S , Hansell, NK , Hariri, AR , Ikram, MK , Jukema, JW , Vuoksimaa, E , Keller, MC , Kremen, WS , Launer, L , Lindenberger, U , Djurovic, Srdjan , Palotie, A , Pedersen, NL , Pendleton, N , Porteous, DJ , Raikkonen, K , Raitakari, OT , Ramirez, A , Reinvang, I , Rudan, I , Rujescu, D , Harris, Sarah E. , Espeseth, Thomas , Schmidt, R , Schmidt, H , Schofield, PW , Schofield, PR , Starr, JM , Steen, VM , Trollor, JN , Turner, ST , Van Duijn, CM , Villringer, A , Giakoumaki, Stella , Weinberger, DR , Weir, DR , Wilson, JF , Malhotra, A , McIntosh, AM , Gale, CR , Seshadri, S , Mosley, TH , Bressler, J , Lencz, T , Giddaluru, S , Deary, IJ , Gustavson, DE , Hayward, C , Hofer, E , Ikram, MA , Karlsson, R , Knowles, E , Lahti, J , Trampush, Joey W. , Leber, M , Li, S , Mather, KA , Melle, I , Morris, D , Oldmeadow, Christopher , Palviainen, T , Payton, A , Pazoki, R , Petrovic, K , Luciano, Michelle , Reynolds, CA , Sargurupremraj, M , Scholz, M , Smith, JA , Smith, AV , Terzikhan, N , Thalamuthu, A , Trompet, S , van der Lee, SJ , Ware, EB , Hill, W. David , Windham, BG , Wright, MJ , Yang, J , Yu, J , Ames, D , Amin, N , Amouyel, P , Andreassen, OA , Armstrong, NJ , Assareh, AA , Hagenaars, Saskia P. , Attia, John R. , Attix, D , Avramopoulos, D , Bennett, DA , Boehmer, AC , Boyle, PA , Brodaty, H , Campbell, H , Cannon, TD , Cirulli, ET , Ritchie, Stuart J. , Congdon, E , Conley, ED , Corley, J , Cox, SR , Dale, AM , Dehghan, A , Dick, D , Dickinson, D , Eriksson, JG , Evangelou, E , Marioni, Riccardo E. , Faul, JD , Ford, I , Freimer, NA , Gao, H , Giegling, I , Gillespie, NA , Gordon, SD , Gottesman, RF , Griswold, ME , Gudnason, V , Fawns-Ritchie, Chloe , Harris, TB , Hartmann, AM , Hatzimanolis, A , Heiss, G , Holliday, Elizabeth G. , Joshi, PK , Kahonen, M , Kardia, SLR , Karlsson, I , Kleineidam, L
- Resource Type: journal article
- Date: 2018
A novel MMP12 locus Is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach
- Creator: Traylor, Matthew , Mäkelä, Kari-Matti , Malik, Rainer , Sudlow, Cathie , Bevan, Steve , Raitoharju, Emma , Oksala, Niku , Thijs, Vincent , Lemmens, Robin , Lindgren, Arne , Slowik, Agnieszka , Kilarski, Laura L. , Maguire, Jane M. , Walters, Matthew , Algra, Ale , Sharma, Pankaj , Attia, John R. , Boncoraglio, Giorgio B. , Rothwell, Peter M. , de Bakker, Paul I. W. , Bis, Joshua C. , Saleheen, Danish , Holliday, ELizabeth G. , Kittner, Steven J. , Mitchell, Braxton D. , Rosand, Jonathan , Meschia, James F. , Levi, Christopher , Dichgans, Martin , Lehtimäki, Terho , Lewis, Cathryn M. , Markus, Hugh S. , Devan, William J. , Nalls, Mike A. , Wiggins, Kerri L. , Zhao, Wei , Cheng, Yu-Ching , Achterberg, Sefanja
- Resource Type: journal article
- Date: 2014
Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures
- Creator: Evans, Tiffany-Jane , Milne, Elizabeth , Richardson, Ebony , Lavis, Laura , Catchpoole, Daniel , Attia, John R. , Armstrong, Bruce K. , Clavel, Jacqueline , Scott, Rodney J. , Anderson, Denise , de Klerk, Nicholas H. , Jamieson, Sarra E. , Talseth-Palmer, Bente A. , Bowden, Nikola A. , Holliday, Elizabeth G. , Rudant, Jéremié , Orsi, Laurent
- Resource Type: journal article
- Date: 2014